Excreted by the kidneys by glomerular filtration and tubular secretion of 85-90% of the dose in unchanged form within 8 hours (most of the drug is excreted within the first hours used, creating a high.. concentration in urine); . 24 anadrol for sale hours is displayed in full (50% – by tubular secretion, 50% – by glomerular filtration).
Therapeutic concentrations are recorded in the pleural fluid, bile, phlegm, myocardium, skin and soft tissues. Cefuroxime concentration exceeding the MIC for the majority of microorganisms can be achieved in bone and synovial intraocular fluids. When meningitis penetrate the BBB. It passes through the placenta, in low concentrations into breast milk.
Bacterial infections caused by susceptible to cefuroxime microorganisms: infections of the respiratory tract (bronchitis, pneumonia, lung abscess, empyema, etc.), Upper respiratory tract (sinusitis, tonsillitis, pharyngitis, otitis media, and others.), Urinary tract ( pyelonephritis, cystitis, symptomatic bacteriuria, gonorrhea and OE), skin and soft tissues (erysipelas, pyoderma, impetigo, furunculosis, cellulitis, wound infection, and pseudoerysipelas anadrol for sale), bones and joints (osteomyelitis, septic arthritis, and OE) pelvic (obstetrics and gynecology), septicemia, meningitis, Lyme disease (Lyme disease), prevention of infectious complications in thoracic organs operations, abdomen, pelvis, joints (in Vol. h. during operations on the lung, heart, esophagus, in vascular surgery at high risk of infectious complications, orthopedic surgery).
Hypersensitivity (r. H. In others. Cephalosporins, penicillins and carbapenems).
Be wary drug use in neonates and premature; during pregnancy and lactation; in debilitated and malnourished patients; in chronic renal failure , diseases of the colon .
Dosing and Administration
In / in and / m adults appoint anadrol for sale 750 mg 3 times a day; in infections of heavy current – increase the dose up to 1500 mg 3-4 times a day (if necessary, the interval between doses can be reduced to 6 hours.).The average daily dose – 3-6 of
Children appoint 30-100 mg / kg / day in 3-4 divided doses. In most infections optimum dose is 60 mg / kg / day. Babies and children up to 3 months. administered 30 mg / kg / day in 2-3 doses.
In gonorrhea – 1500 mg / m once (or in the form of two injections of 750 mg in the introduction of different areas, for example in both gluteal muscle).
In bacterial meningitis – by 3 g / in every 8 h .; children younger and older – 150-250 mg / kg / day in 3-4 hours, the newborn – 100 mg / kg / day.
When pneumonia – 1500 mg / m or / 2-3 times a day for 48-72 hr., then transferred to intake at 500 mg two times a day for 7-10 days.
prescribed to 750 mg / m or / 2-3 times a day during exacerbation of chronic bronchitis for . 48-72 h, then move on ingestion, of 500 mg 2 times a day for 5-10 days. for perioperative prophylaxis in abdominal surgery, pelvic and orthopedic surgery – 1500 mg / in anesthesia induction then further – 750 mg / m after 8 and 16 hours after the operation.. in heart surgery, lung, esophagus and blood vessels – 1500 mg / in anesthesia induction, then – 750 mg / m 3 times . the next day for 24-48 hours in total joint replacement – 1500 mg of powder are dry mixed with each packet methyl methacrylate polymer cement prior to adding the liquid monomer. when CRF requires correction mode: the creatinine clearance 10-20 ml / min administered in / in or / m to 750 mg two times a day, with anadrol for sale less than 10 ml / min – 750 mg 1 time per day. Patients in continuous hemodialysis using arteriovenous shunt or hemofiltration high rate in intensive care units, administered 750 mg 2 times a day; for patients who are at low speed hemofiltration, prescribed dose recommended under impaired renal function.